Description

IL11 is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells.

References
1. Cockrell EM, et.al Cytokine. 2004 Oct 21;28(2):55-8. 2. Dimitriadis E, et.al J Clin Endocrinol Metab. 2005 Jun;90(6):3458-65. Epub 2005 Mar 22.

Specification
Aliases	AGIF; IL-11
Entrez GeneID	3589
Swissprot	P20809
clone	6D9A1
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of human IL-11 expressed in E. Coli.
Formulation	Purified antibody in PBS containing 0.03% sodium azide.

Application
ELISA	1/10000