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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Immunofluorescence analysis of Hela cells using FGF2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Mouse Monoclonal Antibody to FGF2

  • 货号:

    31792
  • 别名:

    BFGF; FGFB; FGF-2; HBGF-2
  • 应用:

    ICC
  • 反应种属:

    Human
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to FGF2

Description

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.

References
1.Stem Cell Reports. 2018 Aug 14;11(2):325-333.
2. Immunol. 2017 Nov 1;199(9):3086-3093.
Specification
Aliases BFGF; FGFB; FGF-2; HBGF-2
Entrez GeneID 2247
Swissprot P09038
clone 1D6B5
WB Predicted band size 30.7kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human FGF2 (AA: 143-288) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Application
ICC 1/200 - 1/1000
ELISA 1/10000