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Mouse Monoclonal Antibody to IL-10

  • 货号:

    20011
  • 别名:

    IL10
  • 应用:

  • 反应种属:

    Human
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to IL-10

Description
Interleukine 10 (IL-10) is a cytokine produced primarily by monocytes and to a lesser extent by
lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-
regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on
macrophages. It also enhances B cell survival, proliferation, and antibody production. This
cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling
pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
References
1. Vieira P, et al. PNAS, 1991.88:1172-1176.
Specification
Aliases IL10
Entrez GeneID 3586
Swissprot P22301
clone 3C12C12
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human IL-10 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Application
ELISA 1/10000
Product Image

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#20011