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CD105

<p>Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)</p>
  • <p>Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)</p>
  • <p>Figure 2:Western blot analysis using CD105 mAb against human CD105 (AA: extra 342-586) recombinant protein. (Expected MW is 42.8 kDa)</p>
  • <p>Figure 3:Western blot analysis using CD105 mAb against HEK293-6e (1) and CD105 (AA: extra 342-586)-hIgGFc transfected HEK293-6e (2) cell lysate.</p>
  • <p>Figure 4:Western blot analysis using CD105 mouse mAb against HUVEC (1), HUVE-12 (2), SH-SY5Y (3), and HEK293 (4) cell lysate.</p>
  • <p>Figure 5:Flow cytometric analysis of THP-1 cells using CD105 mouse mAb (green) and negative control (red).</p>
  • <p>Figure 6:Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using CD105 mouse mAb with DAB staining.</p>
  • <p>Figure 7:Immunohistochemical analysis of paraffin-embedded kidney cancer tissues using CD105 mouse mAb with DAB staining.</p>

图片

  • Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

  • Figure 2:Western blot analysis using CD105 mAb against human CD105 (AA: extra 342-586) recombinant protein. (Expected MW is 42.8 kDa)

  • Figure 3:Western blot analysis using CD105 mAb against HEK293-6e (1) and CD105 (AA: extra 342-586)-hIgGFc transfected HEK293-6e (2) cell lysate.

  • Figure 4:Western blot analysis using CD105 mouse mAb against HUVEC (1), HUVE-12 (2), SH-SY5Y (3), and HEK293 (4) cell lysate.

  • Figure 5:Flow cytometric analysis of THP-1 cells using CD105 mouse mAb (green) and negative control (red).

  • Figure 6:Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using CD105 mouse mAb with DAB staining.

  • Figure 7:Immunohistochemical analysis of paraffin-embedded kidney cancer tissues using CD105 mouse mAb with DAB staining.

CD105
Catalog#   :  32112
Size/Concentration   :  1.0mg/ml
Price:
¥ 2557.5
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1
Instruction:
Specification
Entrez GeneID2022
AliasesENG; END; HHT1; ORW1
Clone#2B2H2
MW70.6kDa
Host/IsotypeMouse IgG1
Storage4℃; -20℃ for long term storage
Species ReactivityHuman;
ImmunogenPurified recombinant fragment of human CD105 (AA: extra 342-586) expressed in E. Coli.
FormulationPurified antibody in PBS with 0.05% sodium azide
Application
ELISA1/10000
WB1/500 - 1/2000
FCM1/200 - 1/400
IHC1/200 - 1/1000
Description
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
References
1.Sci Rep. 2019 Dec 4;9(1):18337.
2.Indian J Pathol Microbiol. 2019 Apr-Jun;62(2):239-243.
Sequence

extra(342-586)


Diagram
Elisa

Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western Blot

Figure 2:Western blot analysis using CD105 mAb against human CD105 (AA: extra 342-586) recombinant protein. (Expected MW is 42.8 kDa)

Western Blot

Figure 3:Western blot analysis using CD105 mAb against HEK293-6e (1) and CD105 (AA: extra 342-586)-hIgGFc transfected HEK293-6e (2) cell lysate.

 

Western Blot

Figure 4:Western blot analysis using CD105 mouse mAb against HUVEC (1), HUVE-12 (2), SH-SY5Y (3), and HEK293 (4) cell lysate.

Flow cytometric

Figure 5:Flow cytometric analysis of THP-1 cells using CD105 mouse mAb (green) and negative control (red).

Immunohistochemical analysis

Figure 6:Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using CD105 mouse mAb with DAB staining.

 

Immunohistochemical analysis

Figure 7:Immunohistochemical analysis of paraffin-embedded kidney cancer tissues using CD105 mouse mAb with DAB staining.

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